Container

ABSTRACT

The invention relates to a container, in particular a plastic ampoule which is produced using a blow moulding process, and which is filled and closed in the production mould, said container having a sleeve-type neck part ( 4 ) connected to a container body ( 2 ) as an axial extension, said neck part forming a seat ( 6 ) for a pre-formed insert ( 8 ) extending along the axis ( 12 ) of the neck part ( 4 ), and said neck part being formed in the production mould, on a peripheral region ( 14 ) of the insert ( 8 ), characterised in that at least one sealing element ( 42; 68 ) is provided on the insert ( 8 ), said sealing element forming a seal in a sealing region surrounding the axis ( 12 ), in combination with a contact surface ( 38 ) formed on the seat ( 6 ) of the neck part ( 4 ).

The invention relates to a container, in particular a plastic ampoulewhich is produced using a blow molding process, and which is filled andclosed in the production mold, said container having a sleeve-type neckpart connected to a container body as an axial extension, said neck partforming a seat for a pre-formed insert extending along the axis of theneck part, and said neck part being formed in the production mold, on aperipheral region of the insert. Moreover, the invention relates to amethod, which is provided in particular for producing such a container.

Containers of this type, in which the container body is made of athermoplastic material such as low-density or high-densitypolypropylene, polyethylene or similar materials that are compatiblewith the intended container contents, are known, cf. WO 2008/098602 A1.Such containers, for example, produced by the known bottelpack® methodare usually used for receiving and delivering fluids for therapeutic orcosmetic purposes, the liquid being delivered via the insert seated inthe neck part of the container body. Its exit or delivery end ispreformed in accordance with the intended use. As shown in the documentmentioned above, in this respect, for example, an exit forming a droppercan be provided for the direct delivery of drops, for instance eyedrops, wherein the dropper opening can be uncovered by unscrewing acontainer closure cap. For delivery via an injection needle, a port foran injection needle or a plastic mandrel can be provided at the deliveryregion of the insert, wherein a perforation region that can be piercedby a mandrel or an injection needle may be formed at the insert.Regardless of the specific design of the delivery region, it may becovered by an end cap or closure cap that is removed from the insertbefore the contents of the container are used.

For safety reasons in the use of such containers, it is decisive that inthe integral molding of the neck part to the adjoining peripheral regionof the insert in the manufacturing mold, said insert is securely fixedin the seat of the neck part in such a way that, even in case of stressapplied to the delivery region of the insert during use, the sealbetween the seat and the insert is not adversely affected and thusleakage, an increased permeation or a microbiological contamination ofthe container contents can be safely ruled out.

With regard to this problem, the invention addresses the problem ofproviding a container of the considered type in which a secure sealbetween the neck part of the container and the insert is ensured andwhich can be used in particular for medical, cosmetic or industrialpurposes, but also for beverages or foods, suitable filling materialsbeing liquids, suspensions, emulsions, ointments, creams or gels.

According to the invention, this object is achieved by a containerhaving the features of claim 1 in its entirety.

According to the characterizing part of claim 1, one essential featureof the invention is that at least one sealing element is provided on theinsert, said sealing element forming a seal in a sealing regionsurrounding the axis in combination with a contact surface formed on theseat of the neck part. If a sealing element is provided on the insert,the process of molding the wall parts of the neck part forming the seatfor the insert can be designed in such a manner that a particularlyreliable sealing connection is formed in the seat.

In a particularly advantageous way, the sealing element can be formed bya molded part of the insert. The container according to the inventioncan be manufactured in a particularly simple, efficient andcost-effective manner for the sealing element formed by a part of theinsert itself, resulting in a corresponding reduction in the expenditurefor providing a separate sealing element.

In particularly advantageous exemplary embodiments of the invention, thearrangement is such that the molded part forming the sealing elementadjoins the end of the peripheral region facing the contact surface ofthe seat, at which peripheral region the neck part is formed onto theinsert. This can be realized in a particularly simple manner using anaxial seal between the seat and the insert.

In a particularly advantageous way, the sealing element can be formed bythe rim of a ring formed on the insert, said rim facing the contactsurface at the seat of the neck part, wherein the ring canadvantageously have the form of an axially protruding rib. In order toensure particularly reliable sealing, the rib can have a shape taperingtowards the rim adjoining the contact surface, to achieve a good sealingeffect in relatively narrow, defined sealing region.

In particularly advantageous exemplary embodiments at least one axiallyprotruding structural part is provided on the insert, displaced radiallyfrom the ring toward the interior, extending beyond it, toward thecontainer body. Because the narrowed collar part formed between the neckpart and the container body contacts the inner wall, a support of theinsert relative to cross forces acting thereon during use is formed. Thestructural part can advantageously have the shape of a coaxial truncatedcone tapering in the direction of the container body, having aconcentric passage in the manner of a bore, opening towards thecontainer body. In doing so, the external conical shape of thestructural part may cling to the shape of the funnel-like collar part ofthe container body.

Alternatively, the arrangement can be such that the insert forms ahollow cylinder within the peripheral region, on the inside wall ofwhich a plurality of axially protruding structural parts are provided inthe form of wings, whose free end regions adjoin the inside of thecollar part.

In advantageous exemplary embodiments, a hollow syringe cone isconnected to the end of the peripheral region of the insert facing awayfrom container body, the cavity of said syringe cone is flush with thecylindrical passage of the truncated cone, from which it is separated bya web, which forms a wall part that can be perforated for extractionpurposes, which can for instance be pierced by a hollow plastic mandrel,a double-ended cannula, similar to DIN EN ISO 7885 or DIN 13097-5, ordouble-pointed injection needles, such as are used for theadministration of insulin.

In further advantageous exemplary embodiments, a lockable connectionpart, having a 6% outer cone (Luer) and a fixedly connected femalethreaded part in accordance with EN 1707:1996 and sealed by a cap, isconnected to the peripheral region of the insert facing away from thecontainer body.

In further advantageous exemplary embodiments, a lockable connectionpart having an outer cone with a closed tip and a firmly connectedfemale threaded part, similar to EN 1707:1996, that is opened bybreaking or twisting the tip off, is connected to the peripheral regionof the insert facing away from the container body.

To secure the insert in the seat by means of integral molding the neckpart to the peripheral region of the insert, to ensure extra protectionagainst both axial forces and against torques, surface irregularitiescan advantageously be formed on the peripheral region of the insert,separated from one another by radially recessed surface sections. Thisresults in a kind of positive locking between the insert and the neckpart of the container body when it is molded thereto.

In the manner known per se for such containers, a closure cap, enclosingthe syringe cone or any other differently shaped extraction area forminga predetermined breaking point to enable the detachment from the neckpart, can be formed to the end of the neck part facing away from thecontainer body. If the insert is secured against acting torques by apositive locking, the cap can be separated in a convenient and secureway by twisting at the predetermined breaking point, wherein a rotaryknob to facilitate a manual twist-off can be integrally formed on theclosure cap, for instance.

The object of the invention is also a method, which is provided inparticular for manufacturing a container according to one of claims 1 to16 and which has the features of patent claim 17.

Below the invention is explained in detail using exemplary embodimentsshown in the drawing.

In the drawings:

FIG. 1 shows the front view of an exemplary embodiment of the inventivecontainer approximately enlarged by factor of 3 in relation to apractical embodiment;

FIG. 2 shows a longitudinal section of the exemplary embodiment, rotatedby 90° in relation to FIG. 1;

FIGS. 3 and 4 show a perspective oblique view or a longitudinal sectionof the insert body of the exemplary embodiment of the container,magnified approximately 2.5-times in relation to FIGS. 1 and 2;

FIGS. 5 and 6 show the insert for a modified exemplary embodiment of thecontainer corresponding to the representations of FIGS. 3 and 4;

FIGS. 7 and 8 show the insert body for a further modified exemplaryembodiment of the container corresponding to the representations ofFIGS. 3 and 4;

FIGS. 9 and 10 show a perspective oblique view or a longitudinal sectionof the insert for a further modified exemplary embodiment, as comparedto FIG. 3 or 4 even more magnified and illustrated broken-off;

FIG. 11 shows a broken-off, perspective oblique view of an insert for astill further modified exemplary embodiment, drawn in the scale of FIGS.9 and 10;

FIG. 12 shows the insert of FIG. 11 in a position mounted on the neckpart of the associated container, in a broken-off and cutrepresentation;

FIG. 13 a perspective oblique view of an exemplary embodiment of thecontainer in the form of a small-volume bottle;

FIG. 14 shows a truncated longitudinal section of the exemplaryembodiment of FIG. 13, wherein only the range of neck part and theclosure cap is depicted;

FIG. 15 shows a longitudinal section of the insert of the exemplaryembodiment of FIG. 8 and a heating device depicted as a diagram, whereinthe state before insertion into the heating device is shown;

FIG. 16 shows a representation corresponding to FIG. 15 with the insertinserted into the heating device;

FIG. 17 shows a longitudinal section of the insert in the state afterheating in the heating device;

FIG. 18 shows a greatly simplified longitudinal section of theblow-molding device for manufacturing a container according to theinvention, wherein a step of the manufacturing process before theinsertion of heated insert is shown;

FIG. 19 shows the production step in which the head jaws of theblow-molding device from FIG. 18 are closed, and

FIG. 20 shows a schematically simplified longitudinal section of thecontainer taken from the blow-molding device.

The invention is described in reference to the drawings, based onexemplary embodiments, in which a container body 2 has a neck part 4,which forms a seat 6 for an insert 8, for the delivery of the liquidpre-stored in the container body 2 when the container is used. In theexamples shown, the container body 2 has the shape of a collapsibleampoule having a cross-section shaped approximately like a rhombus.

The container body 2 made of plastic material by blow molding isdesigned, at a total volume of 2 ml, for a filling volume of 1.5 ml andhas a collar part 10, forming, as a local restriction, the transition tothe sleeve-like neck part 4 having a larger diameter. In doing so, thecollar part 10 has the shape of a funnel, to which, coaxially to acontainer axis 12, the neck part 4 is connected in the form of acircular cylindrical sleeve, concentric to the axis 12.

The insert 8, which is separately shown in FIGS. 3 and 4, has the shapeof an integrally formed rotary body made of plastic, concentric to theaxis 12, wherein preferably the same material, or a material of the sameclass of materials, from which the container body 2, including thecollar part 10 and neck part 4, is made, may be provided. In themanufacturing process according to the bottelpack® method, where aplastic tube is extruded into a blow mold, in which the container body 2including the collar part 10 is formed using main mold jaws and theadjoining container parts, like the neck part and optionally anadjoining cap, are formed using head jaws, the insert 8 is inserted intothe seat 6 of the neck part 4 before the head jaws are closed. Thesubsequent closing of the head jaws, as is usual in the prior art, isused to form the neck part 4 to the associated peripheral region 14 (cf.FIGS. 3 and 4) of the insert 8. In the example shown in FIGS. 1 and 2, aclosure cap 16 is formed to the end of the sleeve part 4, wherein apredetermined breaking point 18 is formed at the transition as adetachable separation point.

As can be seen in FIGS. 3 and 4, the insert 8 has a main part 22, towhich the peripheral region 14 is formed, to which the neck part 4 isformed during the closing of the head jaws. In the performance of thementioned bottelpack® process, this is done after the container contentshave been filled into container body 2 by means of a filling mandrel.Deviating from the form of a smooth cylinder jacket, the main part 22shows surface irregularities at the peripheral region 14, which areformed by radially recessed surface areas 26 next to un-recessed surfaceareas 24. In the example of FIGS. 3 and 4, the recessed surface areas 26are formed by circumferential grooves in the manner of annular groovesextending in the circumferential direction, i.e. the un-recessed surfaceareas 24 are shaped like annular ribs extending at an axial distance toone another. In this shaping of the peripheral region 14, a kind ofserration is created when the neck part 4 is molded to the main part 22of the insert 8, to secure the insert 8 in the seat 6 of the sleeve part4 using the formed positive lock against any acting axial forces. Asyringe cone 28 is formed on the end of the main part 22 of the insert 8facing away from the seat 6, which forms the delivery end of the insert8. In the example shown, the syringe cone 28 has an axial length that isgreater than the length of the main part 22, and has an inner, coaxialcavity 30, which is closed at the end adjoining the main part 22 by across web 32, in which a central, recessed part 34 is formed. A coaxialbore-like passage 36, which is open at the end of the insert 8 facingthe container body 2, is connected to the web 32. The recessed area 34forms a region of reduced wall thickness in the web 32, which serves asperforation area for a hollow plastic mandrel, a double-ended cannuladuring extraction, similar to DIN EN ISO 7885 or DIN 13097-5, to extractcontainer contents through the passage 36.

A step 38 is formed in seat 6 of the neck part 4 at the transition tothe collar part 10 (cf. FIG. 2), which serves as a contact surface for asealing element, which seals the insert 8 in the seat 6. The sealingelement is formed by a molded part of the insert 8 itself. As can bebest seen in FIG. 4, a ring 42 is formed on the end of the peripheralregion 14 facing the container body 2 along the peripheral rim, to whichan axial recess 44 is connected radially inwards in the form of anannular groove, i.e. the ring 42 forms an axially protruding annularrib. It is tapered, as FIG. 4 clearly shows, towards the axiallyprotruding rim, with which it adjoins the contact surface at the step 38of the seat 6, the tapered rib shape of the ring 42 forming aneffective, narrow sealing region.

Radially inwardly from the recess 44, a coaxial truncated cone 46, atthe end of which the bore 36 is open, tapering toward the container body2, adjoins the main part 22. As shown in FIG. 2, in the insertedposition the outer conical surface of the truncated cone 46 adjoins theinside of the funnel-like collar part 10, the truncated cone 46 forminga structural part centering the insert 8 in the seat 6 and supporting itagainst transverse forces.

FIGS. 5 and 6 show a modified exemplary embodiment, which differs fromthe example described above, only by a modified shape of the surfaceirregularities on the peripheral region 14 of the main part 22 of theinsert 8. Instead of the recessed surface areas 26, which extend only inthe circumferential direction, in the example of FIGS. 5 and 6, therecessed surface areas 26 extend both in the circumferential directionand in the axial direction, so that rib parts 52, and not closed annularribs, are formed at the peripheral region.

FIGS. 7 and 8 show an exemplary embodiment with a further modifiedconfiguration of the peripheral region 14 on the insert 8, whichcorresponds to the examples described above, concerning theconfiguration of the sealing element in the form of a ring 42. As shownin FIGS. 7 and 8, a radially protruding annular body 54 having arounded, bead-like shape, from which a crown of circumferentiallydistributed longitudinal ribs 56 extends in the direction of the syringetip 28, is provided in approximately the central longitudinal section ofthe main part 22, wherein the longitudinal ribs 56, however, terminateat a distance in front of the syringe cone 28. The outside of thelongitudinal ribs 56 has a rounded shape, as shown in FIG. 7. In thisconfiguration, having surface irregularities at the peripheral region14, a positive locking is formed between the neck part 4 and the insert8 insert 8 formed thereto, which secures the insert 8, both by means ofthe longitudinal ribs 56 against rotation, and using the annular body54, against axial movement.

FIGS. 9 and 10 show an example still further modified, in which a crownof longitudinal grooves 58 distributed around the periphery is disposedat the peripheral region 14 of the insert 8. Further, as shown in FIG.10, the passage 36, extending in the truncated cone 46 and the cavity30, extending towards the delivery end, are not separated by a radiallyextending transverse web 32, but an inner cone 62 extends from thetruncated cone 46 into the cavity 30. The inner cone 62 is also shapedlike a truncated cone, which is closed at the end located in the cavity30 by a sort of diaphragm 64, which forms the perforation region.

FIGS. 11 and 12 show an exemplary embodiment in which the insert 8 formsa hollow cylinder 66 inside the peripheral region 14, the rim of which,facing the container body 2, forms a ring 68 having a curved surface asa sealing element, adjoining the contact surface at the seat 6 of theneck part 4 formed by the step 38 in a sealing manner. On the outside ofthe hollow cylinder 66, longitudinal ribs 72, which end at a short axialdistance in front of the sealing element forming ring 68, are designedas surface irregularities distributed on the circumference. Axiallyprotruding structural parts in the form of circumferentially distributedwings 74 are formed on the inside of the hollow cylinder 66, whichextend in radial planes, and the free end parts 76 of which contact theinside of the collar part 10 at the mounting position and thus ensure agood axial centering in the seat 6 even for inserts 8 having largerdiameters.

For easy detachment of the over-mold closure cap 16 at the predeterminedbreaking point 18, a rotary knob having laterally projecting handleparts 82, 84 is formed at the end part of the closure cap 16, as shownin FIG. 1.

The respective sealing element can apply the individually requiredsealing effect due to its being inherently stable; but it is alsopossible to melt the sealing element 42, 68, which then forms a solid,fluid-impermeable barrier to the other adjacent plastic material, bythermal input. Possibly resulting excess plastic material from themelting process can be displaced into the hollow groove 44 (cf. FIG. 4)and there serve as an additional filler material for welding, to achievea homogeneous welded joint in this way.

FIGS. 13 and 14 show an alternative embodiment of the container in theform of a small volume vial, intended for a capacity of about 30 ml, inwhich the container body 2 is formed by a bellows, which can becompressed during an extraction process. As FIG. 14 shows, the insert 8,which is inserted as an insert part in the sleeve part 4, has anextraction cone in the form of a male Luer Lock 90. It extends coaxiallywithin a sleeve part 89, the outside of which constitutes the peripheralpart, to which the neck part 14 is formed. The Luer Lock 90 protrudingbeyond the end of the sleeve part 89 has a closure part 92 for closingits outlet opening, which is formed to the Luer Lock 90 over apredetermined breaking point 91. The closure part 92 has an axiallyprotruding bar element 93, which is tightly enclosed by the overmoldclosure cap 16. In this way, a rigid connection is created, i.e. theclosure part 92 can be safely taken off by means of releasing thepredetermined breaking point 91 and the separation point 18 togetherwith the overmold closure cap 16 by twisting off the latter using therotary levers 82, 84 integrally formed thereon.

FIGS. 15 to 17 illustrate steps of the method according to the inventionwhich enable a particularly high anti-microbial sealing effect to beobtained between the insert 8 and the container body 2 duringmanufacture of the container. In this respect, the procedure is suchthat the insert 8, in particular in the area of the ring 42 forming thesealing element, is heated to a temperature of at least 50° to 70°Celsius before the insertion into the seat 6 of the neck part 4 duringthe manufacture of the container according to the bottelpack® process.In this way, the formation of the fusion bond during the closing of thehead jaws 97 (FIGS. 18 to 20) is facilitated. FIGS. 15 to 17 illustratethe procedure. Immediately prior to insertion into the blow-moldingdevice, the insert 8 is preheated by a heating device, which in FIGS. 15and 16 is designed as a so-called heat reflector 94. FIG. 15 shows thestate before contact with the heat reflector 94, while FIG. 16illustrates the heating process. Preheating can be done by directcontact of the sealing element 42; 68 using a heated surface or byradiating heat, for instance using infrared rays or laser beams, or, ifthe insert 8 is made from correspondingly additized plastics, also byinductive coupling of an electromagnetic field. To promote the formationof the fusion bond, the insert 8 also can be composed of severaldifferent materials, e.g. produced by multicomponent injection molding.The sealing element 42; 68, for instance, may be formed from athermoplastic polymer softening at low temperatures and having goodadhesion properties to the polymer material of the container body 2, inparticular a thermoplastic elastomer can be provided (TPE) for thispurpose. The other parts of the insert 8 can be made of polymers havinghigher softening temperatures. In this way, a high dimensional stabilityof the insert 8 is ensured as well as a tight connection by melting,even at warming to higher temperatures. To achieve a particularly highmicrobiological tightness after being subjected to mechanical torsionalstress, it is advantageous if the sealing element 42 is located outsidethe area of the circumferential surface irregularities 24, 26; 52; 54;56; 58; 72 located on the insert 8, to prevent the torsionalmoments/forces, for instance during opening, from significantlyaffecting the sealing element 42.

FIGS. 18 to 20 show the manufacturing steps downstream of the heatingprocess. FIG. 18 shows the insert 8 immediately before the insertionprocedure. During the insertion, at first merely an axial pressure forceis applied to the insert 8, to ensure a fusion bond, upon which radialforces are applied after a time delay by closing the head jaws 97, toachieve the interlocking between the surface irregularities of theperipheral region of the insert 8. A short delay of even less than onesecond between these operations has a particularly advantageous effect.FIG. 19 shows the state after the head jaws 97 have been closed, whereinthe over-mold closure cap 16 is formed and sealed to produce the closedstate of the container as shown in FIG. 20.

For the process of heating, the following temperature ranges have provenuseful if suitable materials were used for the tube 98 forming thecontainer and the insert 8 with sealing element 42; 68:

Container Material: Insert/Sealing Element Temperature Sealing LDPELDPE/LDPE up to 95-120° C. LDPE HDPE/HDPE up to 130-145° C. PP PP/PP upto 150-170° C. PET PET/PET (amorphous) up to 70-100° C. PP PP/TPE up to120-160° C.

1. A container, in particular a plastic ampoule, which is produced usinga blow molding process, and which is filled and closed in the productionmold, said container having a sleeve-type neck part (4) connected to acontainer body (2) as an axial extension, said neck part forming a seat(6) for a pre-formed insert (8) extending along the axis (12) of theneck part (4), and said neck part being formed in the production mold,on a peripheral region (14) of the insert (8), characterized in that atleast one sealing element (42; 68) is provided on the insert (8), saidsealing element forming a seal in a sealing region surrounding the axis(12), in combination with a contact surface (38) formed on the seat (6)of the neck part (4).
 2. The container according to claim 1,characterized in that the sealing element (42; 68) is formed by a moldedpart of the insert (8) associated with the latter.
 3. The containeraccording to claim 1, characterized in that the sealing element (42; 68)adjoins the end of the peripheral region (14), on which the neck part(4) to the insert (8) is formed, facing the contact surface (38) of theseat (6).
 4. The container according to claim 1, characterized in thatthe sealing element (42; 68) is formed by the edge of a ring (42; 68)formed on the insert (8) facing the contact surface (38) on the seat (6)of the neck part (4).
 5. The container according to claim 1,characterized in that the ring-shaped sealing element (42) has the formof an axially protruding rib.
 6. The container according to claim 1,characterized in that the sealing element (42) is rib-shaped and has ashape tapering towards the rim adjoining the bearing surface (38). 7.The container according to claim 1, characterized in that at least oneaxially protruding structural part (46; 74) is provided on the insert(8) extending offset radially inwards to the annular sealing element(42; 68) and beyond the former towards the container body (2).
 8. Thecontainer according to claim 1, characterized in that the axiallyprotruding structural part has the shape of a coaxial truncated cone(46) tapering in the direction of the container body (2), which has aconcentric passage (36) that is open towards the container body (2). 9.The container according to claim 1, characterized in that the insert (8)forms a hollow cylinder (66) within the peripheral region (14), on theinner wall of which a plurality of axially protruding structure parts inthe form of circumferentially arranged distributed wings (74) areprovided, the free end regions (76) of which contact the inside of thecollar part (10).
 10. The container according to claim 1, characterizedin that a hollow syringe cone (28) is connected at the end of theperipheral region (14) of the insert (8) facing away from the containerbody (2), the cavity (30) of which is flush with the bore-like passage(36) of the truncated cone (46), from which it is separated by a web(32) forming a wall part (34) that can be pierced for an extractionprocess.
 11. The container according to claim 1, characterized in thatthere are surface irregularities (24, 26; 52; 54; 56; 58; 72) at theperipheral region (14) of the insert (8), which are formed by surfaceparts separated from each other by radially recessed or raised surfaceareas and arranged axially offset to the annular sealing element (42)towards the cone (28).
 12. The container according to claim 1,characterized in that an over-mold closure cap (16) enclosing thesyringe cone (28) is formed to the end of the neck part (4) facing awayfrom the container body (2) forming a predetermined breaking point (18)enabling the separation from the neck part (4).
 13. The containeraccording to claim 1, characterized in that an integral, male Luer Lock(40) is formed on the insert (8), said Luer Lock having a closure part(92) connected to the over-mold closure cap (16) and when it is removed,can be removed together with the latter at a separation point (91) atthe end of the Luer Lock (90), for opening the cone at the upper end ofits cone (28).
 14. The container according to claim 1, characterized inthat the closure part (92) comprises a bar (93) extending axially awayfrom the cone (28), integrated in the region of the handle parts (82,84) serving as a turn-off knob in the over-mold closure cap (16). 15.The container according to claim 1, characterized in that the insert (8)is formed of at least two different materials, of which at least one issoftenable at low temperatures.
 16. The container according to claim 1,characterized in that the softenable material is a thermoplastic polymerhaving good adhesion properties to the polymer material of the containerbody, in particular a thermoplastic elastomer (TPE), and that there isanother polymeric material having a higher softening temperature.
 17. Amethod, which is provided in particular for the manufacture of acontainer according to claim 1, characterized in that the sealingelement (42; 68) of the insert (8) is energetically treated, inparticular heated, before its insertion into the blow-molding device(97, 99).
 18. The method according to claim 17, characterized in thatthe operation of inserting the insert (8) in the blow-molding device(97, 99) is performed such that at first only an axial pressure force isapplied, to ensure a fusion bond of the sealing element (42; 68) on theseat (6) of the neck part (4), and that then, delayed, radial forces areapplied by closing of the head jaws (97) to achieve the serration of thesurface irregularities (24, 26; 52; 54; 56; 58; 72) of the peripheralregion (14).